Gender discrepancies in the diagnostic processes of Autism Spectrum Disorder: A systematic literature review of the silenced girls

Authors

  • María García González Albizu University

Keywords:

autism spectrum disorder, female gender, diagnosis, methods of evaluation, systematic literature review

Abstract

The article is a systematic literature review (SLR) that investigates the characteristics of the diagnosis of autism spectrum disorder (ASD) in the female gender and whether diagnostic evaluation processes should be different for each gender. The research questions are: What characteristics are identified in girls with ASD, which could be considered to establish new guidelines in diagnostic processes? and, what diagnostic instruments are used to identify and confirm a diagnosis of ASD, which considers gender differences in its process? A boolean search method was implemented for the SLR by the Ebscohost metasearch engine. Eight articles (n=8) from five countries were used. The investigations demonstrated patterns of behavior presented by the female gender as compensatory behaviors and masking. The results detailed differences in the proportion of girls who met particular screening criteria, but did not meet all the criteria necessary to receive an autism diagnosis. It was determined that more research is required on how to implement diversity in evaluation methods considering the particularities of the genders.

References

Albores Gallo, L., Hernández Guzmán, L., Díaz Pichardo, J. A., & Cortes Hernández, B. (2008). Dificultades en la evaluación y diagnóstico del autismo. Una discusión. Salud Mental, 31(1), 37–44.

American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.).

American Psychiatric Association. (2022). Diagnostic and statistical manual of mental disorders. (5th ed., text rev.).

Artigas-Pallares, J., & Paula, I. (2012). El autismo 70 años después de Leo Kanner y Hans Asperger. Revista de la Asociación Española de Neuropsiquiatría, 32(115), 567–587. https://doi.org/10.4321/s0211-57352012000300008

Begeer, S., Mandell, D., Wijnker-Holmes, B., Venderbosch, S., Rem, D., Stekelenburg, F., & Koot, H. M. (2013). Sex differences in the timing of identification among children and adults with autism spectrum disorders. Journal of Autism and Developmental Disorders, 43(5), 1151–1156. https://doi.org/10.1007/s10803-012-1656-z

Bud Craig, A. (2003). Interoception: the sense of the physiological condition of the body. Current Opinion in Neurobiology, 13(4), 500–505.

Centro para Control y Prevención de Enfermedades. (2018, Noviembre 15). Data & Statistics on Autism Spectrum Disorder. https://www.cdc.gov/ncbddd/autism/data.html

Consorcio de Bibliotecas Metropolitanas. (2012). About us. https://cobimet.org/cbm/en/

Craig, F., Fanizza, I., Russo, L., Lucarelli, E., Alessandro, L., Pasca, M. G., & Trabacca, A. (2017). Social communication in children with autism spectrum disorder (ASD): Correlation between DSM-5 and autism classification system of functioning-social communication (ACSF:SC). Autism Research, 10(7), 1249–1258.

Dean, M., Harwood, R., & Kasari, C. (2017). The art of camouflage: Gender differences in the social behaviors of girls and boys with autism spectrum disorder. Autism, 21(6), 678–689. https://doi.org/10.1177/1362361316671845

Díaz Balado, A. (2012). El proceso de visibilización de las mujeres con discapacidad: Diferencia y perfil. Revista Internacional de Ciencias Humanas, 1(2).

Dworzynski, K., Ronald, A., Bolton, P., & Happé, F. (2012). How different are girls and boys above and below the diagnostic threshold for autism spectrum disorders? Journal of the American Academy of Child & Adolescent Psychiatry, 51(8), 788–797. https://doi.org/10.1016/j.jaac.2012.05.018

Gardner, L. M., Campbell, J. M., Keisling, B., & Murphy, L. (2018). Correlates of DSM-5 autism spectrum disorder levels of support ratings in a clinical sample. Journal of Autism and Developmental Disorders, 48(10), 3513–3523.

Goddard, L., Dritschel, B., & Howlin, P. (2014). A preliminary study of gender differences in autobiographical memory in children with an autism spectrum disorder. Journal of Autism and Developmental Disorders, 44(9), 2087–2095.

Gough, D., Oliver, S., & Thomas, J. (2013). Learning from research: Systematic reviews for informing policy decisions. Analysis & Policy Observatory.

Gould, J. (2017). Towards understanding the under-recognition of girls and women on the autism spectrum. Autism, 21(6), 703–705. https://doi.org/10.1177/1362361317706174

Halladay, A. K., Bishop, S., Constantino, J. N., Daniels, A. M., Koenig, K., Palmer, K., Messinger, D., Pelphrey, K., Sanders, S. J., Singer, A. T., Taylor, J. L., & Szatmari, P. (2015). Sex and gender differences in autism spectrum disorder: summarizing evidence gaps and identifying emerging areas of priority. Molecular Autism, 6(1).

Haney, J. L. (2016). Autism, females, and the DSM-5: Gender bias in autism diagnosis. Social Work in Mental Health, 14(4), 396–407. https://doi.org/10.1080/15332985.2015.1031858

Kentrou, V., de Veld, D. M., Mataw, K. J., & Begeer, S. (2019). Delayed autism spectrum disorder recognition in children and adolescents previously diagnosed with attention-deficit/hyperactivity disorder. Autism, 23(4), 1065–1072.

Khan, K. S., Kunz, R., Kleijnen, J., & Antes, G. (2003). Five steps to conducting a systematic review. Journal of the Royal Society of Medicine, 96(3), 118–121. https://doi.org/10.1258/jrsm.96.3.118

Lai, M. C., Lombardo, M. V., Ruigrok, A. N., Chakrabarti, B., Auyeung, B., Szatmari, P., Happé, F., & Baron-Cohen, S., & MRC AIMS Consortium (2017). Quantifying and exploring camouflaging in men and women with autism. Autism, 21(6), 690–702.

Lawson, W. (2007). Sensory Issues in Autism. https://www.viva-access.com/wp-content/uploads/2016/10/Sensory-Issues-in-Autism-East-Sussex.pdf

Lehnhardt, F.-G., Falter, C. M., Gawronski, A., Pfeiffer, K., Tepest, R., Franklin, J., & Vogeley, K. (2015). Sex-related cognitive profile in autism spectrum disorders diagnosed late in life: Implications for the female autistic phenotype. Journal of Autism and Developmental Disorders, 46(1), 139–154. https://doi.org/10.1007/s10803-015-2558-7

Loomes, R., Hull, L., & Mandy, W. P. L. (2017). What is the male-to-female ratio in autism spectrum disorder? A systematic review and meta-analysis. Journal of the American Academy of Child & Adolescent Psychiatry, 56(6), 466–474.

Maenner, M. J., Wiggins, L., Christensen, D. L., Baio, J., Daniels, J., Warren, Z., Kurzius-Spencer, M., Zahorodny, W., Robinson Rosenberg, C., White, T., Durkin, M. S., Imm, P., Nikolaou, L., Yeargin-Allsopp, M., Lee, L.-C., Harrington, R., Lopez, M., Fitzgerald, R. T., Hewitt, A., …Dowling, N. F. (2018). Prevalence of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2014. MMWR. Surveillance Summaries, 67(6), 1–23.

Mattila, M. L., Kielinen, M., Linna, S. L., Jussila, K., Ebeling, H., Bloigu, R., Joseph, R. M., & Moilanen, I. (2011). Autism spectrum disorders according to DSM-IV-TR and comparison with DSM-5 draft criteria: An epidemiological study. Journal of the American Academy of Child & Adolescent Psychiatry, 50(6), 583-592.

Milner, V., McIntosh, H., Colvert, E., & Happé, F. (2019). A Qualitative Exploration of the female experience of autism spectrum disorder (ASD). Journal of Autism and Developmental Disorders, 49(6). https://doi.org/10.1007/s10803-019-03906-4

Onwuegbuzie, A. J., Leech, N. L., & Collins, K. M. (2012). Qualitative Analysis Techniques for the Review of the Literature. The Qualitative Report, 17(28), 1–28.

Valencia Prado, M., Nieves Muñoz, N., & Irrizary Mayoral, L. (2018). Guía para la identificación temprana de trastornos del espectro del autismo. Departamento de Salud de Puerto Rico: División Niños con Necesidades Médicas Especiales.

Ratto, A. B., Kenworthy, L., Yerys, B. E., Bascom, J., Wieckowski, A. T., White, S. W., Wallace, G. L., Pugliese, C., Schultz, R. T., Ollendick, T. H., Scarpa, A., Seese, S., Register-Brown, K., Martin, A., & Anthony, L. G. (2018). What about the girls? Sex-based differences in autistic traits and adaptive skills. Journal of Autism and Developmental Disorders, 48(5), 1698–1711. https://doi.org/10.1007/s10803-017-3413-9

Rivet, T. T., & Matson, J. L. (2011). Gender differences in core symptomatology in autism spectrum disorders across the lifespan. Journal of Developmental and Physical Disabilities, 23(5), 399–420.

Rynkiewicz, A., & Łucka, I. (2018). Autism spectrum disorder (ASD) in girls. Co-occurring psychopathology. Sex differences in clinical manifestation. Psychiatria Polska, 52(4), 629–639.

Seldas, R. P. (2012). Los síntomas de los trastornos del espectro de autismo en los primeros dos años de vida: una revisión a partir de los estudios longitudinales prospectivos. Anales de Pediatría, 76(1), https://doi.org/10.1016/j.anpedi.2011.07.033

Solomon, M., Miller, M., Taylor, S. L., Hinshaw, S. P., & Carter, C. S. (2012). Autism symptoms and internalizing psychopathology in girls and boys with autism spectrum disorders. Journal of Autism and Developmental Disorders, 42(1), 48–59.

Suckle, E. K. (2021). DSM-5 and Challenges to Female Autism Identification. Journal of Autism and Developmental Disorders. 51(2), 754–759.

The Editors of Encyclopedia Britannica. (2020). Boolean Algebra. https://www.britannica. com/topic/Boolean-algebra

Organización Mundial de la Salud. (2019). Autism spectrum disorders. https://www.who.int/news-room/fact-sheets/detail/autism-spectrum-disorders#:~: text=It%20is%20

Organización Mundial de la Salud. (2019, Junio 19). Gender. https://www.who.int/health-topics/gender

Zurynski, Y. (2014). Writing a Systematic Literature Review: Resources for Students and Trainees.

Published

2023-04-01